Compound
Active substance:
Timolol maleate – 6.83 mg (corresponds to timolol 5.0 mg).
Excipients:
Benzalkonium chloride solution (50%) corresponds to benzalkonium chloride,
povidone K 30,
sodium dihydrogen phosphate dihydrate,
sodium monohydrogen phosphate dodecahydrate,
disodium edetate dihydrate,
water for injections.

Indications
     Angle-closure glaucoma (in combination with miotics as an additional means to reduce IOP).
     Congenital glaucoma (with insufficient effectiveness of other therapeutic measures).
     Open angle glaucoma.
     Secondary glaucoma (including aphakic).
     Increased intraocular pressure (ocular hypertension).

Use during pregnancy and breastfeeding
Arutimol is contraindicated during pregnancy, breastfeeding and early childhood.

Contraindications
     Hypersensitivity to timolol.
     Allergic reactions with generalized skin rashes.
     Chronic obstructive respiratory diseases (including bronchial asthma).
     Severe heart failure.
     Sinus bradycardia.
     AV block II or III degree.
     Cardiogenic shock.
     Corneal dystrophy.
     Severe atrophic rhinitis.

Use the drug with caution in the following cases:
     In patients with thyrotoxicosis.
     In patients with chronic bronchitis and emphysema.
     In patients with diabetes mellitus receiving insulin or oral hypoglycemic agents (the use of timolol can lead to hypoglycemia).

Side effects
     heart failure
     heart rhythm disturbances
     shortness of breath, muscle weakness, decreased blood pressure
     headache, sleep disturbances, depression
     nausea, vomiting, diarrhea
     skin allergic reactions
     burning in the eyes.

How to take, course of administration and dosage
Arutimol eye drops are instilled 1-2 drops 1-2 times a day.
After stabilization of IOP, it is possible to reduce the dose to 1 drop 1 time/day.

Storage conditions
In a place protected from light, at a temperature not exceeding 25 °C.

Best before date
36 months. After opening the bottle - 6 weeks.