Compound
Active substance:
domperidone 10 mg;

Indications
A complex of dyspeptic symptoms associated with delayed gastric emptying, gastroesophageal reflux, esophagitis: a feeling of fullness in the epigastrium, a feeling of bloating, pain in the upper abdomen; belching, flatulence; heartburn with or without reflux of stomach contents into the oral cavity.
Nausea and vomiting of functional, organic, infectious origin, caused by radiotherapy, drug therapy or diet disorders, as well as against the background of dopamine agonists (for example, levodopa and bromocriptine), if used for Parkinson's disease.

Use during pregnancy and breastfeeding
It can be used in the first trimester of pregnancy if the expected effect of therapy exceeds the potential risk to the fetus. Breastfeeding should be stopped during treatment (it is not known whether the drug has a negative effect on newborns).
When administered to animals in doses up to 160 mg/kg/day, domperidone did not have a teratogenic effect. To date, there is no evidence of an increased risk of developmental defects in humans. In women, concentrations of domperidone in breast milk are 4 times lower than the corresponding concentrations in plasma.

Contraindications
Hypersensitivity, gastrointestinal bleeding, mechanical intestinal obstruction, perforation of the stomach or intestines, prolactin-secreting tumor of the pituitary gland (prolactinoma), children under 5 years of age.
With caution: liver/renal failure.

Side effects
From the digestive system: transient intestinal spasms.
From the nervous system: extrapyramidal disorders (in children and people with increased permeability of the BBB).

Allergic reactions:
  skin rash, urticaria.
Other: hyperprolactinemia (galactorrhea, gynecomastia).


Storage conditions
In a dry place, protected from light, at a temperature not exceeding 25 °C

Best before date
2 years